Retrograde ejaculation - Overview

Even though the sexual climax is attained, very little semen or no semen is released. One of the major reasons for such issues can be retrograde ejaculation. Retrograde ejaculation is defined as the condition where the sperms do not flow out of the penis instead move backward towards the bladder to mix with urine during ejaculation.

This condition is also referred to as dry orgasm and can cause infertility in men. The absence of ejaculate and cloudy urine after ejaculation can indicate retrograde ejaculation.

What causes azoospermia?

The bladder opening is guarded by a muscle called the sphincter muscle that tightens, preventing the movement of sperms into the bladder. The sphincter muscle also helps hold the urine in the bladder until urination. In retrograde ejaculation, the sphincter muscle can loosen up causing the backward flow of semen. Several conditions can cause sphincter muscle dysfunction. They are:

  • Prior surgery, such as bladder neck surgery, surgery for testicular cancer, or prostate cancer.
  • Surgical removal of the prostate (prostatectomy) or bladder (cystectomy)
  • Side effects of certain medications used to treat high blood pressure, depression, and prostate inflammation.
  • Nerve damage caused due to diabetes, Parkinson’s disease, multiple sclerosis, spinal cord injuries, or accidental injuries.
  • Radiotherapy, performed while treating cancer of the pelvic organs.

How is retrograde ejaculation diagnosed?

Diagnosis for retrograde ejaculation involves a complete understanding of the medical history followed by physical examination and urinalysis done after ejaculation to check the presence of sperms in the collected urine sample.

How can retrograde ejaculation be treated?

Treatment for retrograde ejaculation depends on the reason causing it.


• Treatment for retrograde ejaculation caused due to damage of nerves includes medications.
• Medications can also help keep the sphincter muscle closed during ejaculation. Some of the medications used are:

  • Imipramine (Tofranil)
  • Midodrine
  • A few antihistamines such as Chlorpheniramine and brompheniramine
  • Certain decongestants like Ephedrine, pseudoephedrine, and phenylephrine

Treatment at OMYA

OMYA specializes in infertility treatment doctors and treatment for retrograde ejaculation at OMYA begins with an accurate diagnostic procedure followed by medications depending on the condition. However, fertility treatment required for retrograde ejaculation is the extraction of sperms from the urine sample collected. The urine sample is primarily processed in the laboratory before extraction.

After the extraction protocol, the sperms can be inseminated into the female reproductive tract either by Intrauterine insemination (IUI) or by Assisted Reproductive Technique (ART). In Vitro Fertilization (IVF), an advanced ART procedure where the sperm is fertilized with a retrieved egg in an incubated condition. The fertilized egg is later transferred into the woman’s uterus for implantation and pregnancy.

At OMYA, a dedicated and experienced team of specialists can guide you through your fertility issues and help you through your pregnancy journey.

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    We neither support nor practice sex / gender selection during any kind of treatment including IVF. We strongly condemn sex / gender selection in any form of treatment.


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